XAV 939

Catalogue number C262582
Chemical nameXAV 939
CAS Number284028-89-3
Synonyms1,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one; NVP-XAV 939;
Molecular WeightC14H11F3N2OS
Formula312.31
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsA tankyrase (TNKS) inhibitor that antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. XAV 939 inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1.
ReferencesHuang, S. et al.: Nature, 461, 614 (2009); Wang, H. et al.: ACS Chem. Biol., 6, 192 (2011); Adles, M.E. et al.: Sci. Signal., 91, ec326 (2009);
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XAV 939
Price(USD)
SizePrice(USD)Discount
5mg$50.0010% OFF
100mg$405.0010% OFF
25mg$110.0010% OFF
250mg$920.0010% OFF
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