Saikosaponin A

Catalogue number C108863
Chemical nameSaikosaponin A
CAS Number20736-09-8
Synonyms(3beta,4alpha,16beta)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl-6-deoxy-3-o-beta-dglucopyranosyl- beta-d-galactopyranoside; (3beta,13alpha,16beta,17alpha)-16,23-dihydroxy-13,28-epoxyolean-11-en-3-yl 6-deoxy-3-O-beta-D-glucopyranosyl-beta-D-galactopyranoside
Molecular WeightC42H68O13
Formula780.9
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications

Saikosaponin A as antioxidants improve antioxidant status. Supplementation with curcumin and/or saikosaponin A suppress inflammation and fibrogenesis in rats with CCl(4)-induced liver injury. However, the combination has no additive effects on anti-inflammation and antifibrosis.


Saikosaponin A possesses a weak inhibitory activity on histamine-induced tracheal contraction in guinea-pigs and on histamine release induced by A-23187 in rat mast cells. These results indicate that Saikosaponin A has an inhibitory activity against allergic asthma. This activity seems to derive from both antagonism of the histamine action and inhibition of allergic mediators.


Saikosaponin A in 50-ug/ml quantities inhibited the cell growth and DNA synthesis of all the cell lines tested.

References1. J. Sep. Sci., 2009, 32, 74-78.
2. J. Chem. Soc., Perkin Trans. 1, 1975, 2043-2048.
3. Journal of Chromatography A, 2010, 1217(26), 4347-4354.
4. Planta Med., 1985, 51(3), 208-212.
5. Am J Chin Med., 2010, 38(1), 99-111.
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Saikosaponin A
Price(USD)
SizePrice(USD)Discount
5mgInquiryN/A
10mgInquiryN/A
25mgInquiryN/A
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