| Catalogue number |
C104657 |
| Chemical name | Methylenetanshinquinone |
| CAS Number | 67656-29-5 |
| Synonyms | 1-methyl-6-methylidene-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione |
| Molecular Weight | C18H14O3 |
| Formula | 278.3 |
| Purity | 98% |
| Physical Description | Red powder |
| Solvent | Chloroform, Dichloromethane,DMSO |
| Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
| Applications | Antioxidative.
A dichloromethane extract of Salvia miltiorrhiza roots was active against both Trypanosoma brucei rhodesiense and Plasmodium falciparum. Subsequent isolation and structure elucidation yielded the known substances miltirone (1), tanshinone II a (2), 1,2 dihydrotanshinquinone (3), methylenetanshinquinone (4), 1-oxomiltirone (5), 11-hydroxymiltiodiol (6), tanshinone I (7), methyltanshinonate (8), and cryptotanshinone (9). The IC50s of the compounds were determined against the two parasites and rat myoblast (L6) cells. They ranged from 4.1 uM to over 30 uM against P. falciparum K1 strain with selectivity indices (SI) from 0.3 to 1.9. IC50s against T. brucei rhodesiense STIB 900 were from 0.5 uM (1, 4) to over 30 uM, and 4 showed the greatest selective activity with an SI of 24.
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| References | 1. Rapid Communications in Mass Spectrometry, 2006, 20(8), 1266-1280.
2. Journal of Chromatography A, 1991, 542, 317-326.
3. J. Agric. Food Chem., 1990, 38(5), 1194-1197.
4. Planta Med., 2011, 77(14), 1594-1596.
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The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
| Size | Price(USD) | Discount |
| 5mg | Inquiry | N/A |
| 10mg | Inquiry | N/A |
| 25mg | Inquiry | N/A |
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