Liquiritigenin

Catalogue number C108572
Chemical nameLiquiritigenin
CAS Number578-86-9
Synonyms7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
Molecular WeightC15H12O4
Formula256.2
Purity98%
Physical DescriptionCryst.
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications

Liquiritigenin is a kind of flavonoids existed in R. glycyrrhizae, with the polyphenolic structure. It has been reported that liquiritigenin could possess cytotoxic activity against five human cancer cell lines in vitro. Also found liquiritigenin inhibited the cell growth of SGC-7901 and Lovo. Due to the polyphenolic structure of liquiritigenin, our study would also demonstrate that either prooxidative or antioxidative activity is involved in the effect of liquiritigenin on SMMC-7721 cells.


Liquiritigenin is an estrogenic compound which acts as an agonist selective for the β-subtype of the estrogen receptor. It also has a choleretic effect.

References1. Cellular and Molecular Life Sciences, 2000, 57(3), 500-505.
2. International Immunopharmacology, 2009, 9(5), 632–638.
3. European Journal of Medicinal Chemistry, 2010, 45(8), 3453-3458.
4. Molecular and Cellular Endocrinology, 2008, 283 (1-2), 49-57.
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Liquiritigenin
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