Fangchinoline

Catalogue number C108623
Chemical nameFangchinoline
CAS Number436-77-1
Synonyms(+)-Hanfangichin B; 6,6’,12-trimethoxy-2,2’-dimethylberbaman-7-ol; (1beta)-6,6’,12-Trimethoxy-2,2’-dimethylberbaman-7-ol; 6,6’,12-trimethoxy-2,2’-dimethylberbaman-7-ol
Molecular WeightC37H40N2O6
Formula608.7
Purity98%
Physical DescriptionCryst.
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsFangchinoline selectively bound to G-quadruplex DNA.
Fangchinoline is a novel anti-tumour agent with little known of its cellular and molecular mechanisms of action. Fangchinoline is a highly specific agent inducing autophagic cell death in hepatocellular carcinoma cells with a novel mechanism, which elucidates the potential of fangchinoline to potentiate programmed cell death in cancer cells.
References1. Chemistry of Natural Compounds, 2000, 36(2), 223-224.
2. Acta Chimica Sinica, 1986, 4(1), 55-61.
3. Journal of Ethnopharmacology, 2000, 69(2), 173-179.
4. British Journal of Pharmacology, 2011, 164(2b), 731-742.
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Fangchinoline
Price(USD)
SizePrice(USD)Discount
5mgInquiryN/A
10mgInquiryN/A
25mgInquiryN/A
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