| Catalogue number | C104159 |
| Chemical name | Desmethylxanthohumol |
| CAS Number | 115063-39-3 |
| Synonyms | (E)-3-(4-hydroxyphenyl)-1-[2,4,6-trihydroxy-3-(3-methylbut-2-enyl)phenyl]-2-propen-1-one |
| Molecular Weight | C20H20O5 |
| Formula | 340.4 |
| Purity | 98% |
| Physical Description | Cryst. |
| Solvent | Chloroform, Dichloromethane,DMSO |
| Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
| Applications | High density lipoprotein (HDL)-cholesterol levels are correlated with a low risk of atherosclerosis. The inhibition of cholesteryl ester transfer protein (CETP), which catalyses cholesterol transfer between lipoproteins, leads to an increase in HDL-cholesterol and is expected to be the next anti-atherogenic target. Xanthohumol showed the highest inhibition against CETP from screening of natural products in various plants. We investigated the inhibitory activity of some chalcones and flavanones. Naringenin chalcone showed weak CETP inhibition compared with xanthohumol. In addition, isoxanthohumol and naringenin drastically decreased the inhibitory activity. These results suggest that the prenyl group and chalcone structure of xanthohumol were responsible for the CETP inhibitory activity. |
| References | 1. Food Chemistry, 2012, 134(3), 1432-1437. 2. Planta Med., 2009, 75(7), 757-762. 3. Phytochemistry, 2004, 65(10), 1317-1330. 4. J. Agric. Food Chem., 2003, 51(15), 4436-4441. 5. Archiv der Pharmazie, 1988, 321(1), 37-40. |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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To place an order, please provide the following information.
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Sent to your order to our email: info@coompo.com
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