| Catalogue number |
C104062 |
| Chemical name | Delphinidin-3-sambubioside chloride |
| CAS Number | 53158-73-9 |
| Synonyms | Delphinidin 3-sambubioside |
| Molecular Weight | C26H29O16Cl |
| Formula | 633.0 |
| Purity | 98% |
| Physical Description | Powder |
| Solvent | Chloroform, Dichloromethane,DMSO |
| Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
| Applications | Antioxidant.
Delphinidin 3-sambubioside (Dp3-Sam) could induce a dose-dependent apoptosis in human leukemia cells (HL-60) as characterized by cell morphology, DNA fragmentation, activation of caspase-3, -8, and -9, and inactivation of poly(ADP)ribose polymerase (PARP). Molecular data showed that Dp3-Sam induced Bid truncation, mitochondrial membrane potential (DeltaPsi(m)) loss, and cytochrome c release from mitochondria to cytosol. Moreover, Dp3-Sam caused a time- and dose-dependent elevation of intracellular reactive oxygen species (ROS) level in HL-60 cells, and antioxidants such as N-acetyl-L-cysteine (NAC) and catalase could effectively block Dp3-Sam-induced ROS generation, caspase-3 activity, and DNA fragmentation. These data indicate that Dp3-Sam might induce apoptosis in HL-60 cells through a ROS-mediated mitochondrial dysfunction pathway.
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| References | 1. Chromatographia, 2011, 74(5-6), 367-373.
2. J. Agric. Food Chem., 1990, 38(3), 708-715.
3. Arch Biochem Biophys., 2005, 440(1), 101-109.
4. Journal of Ethnopharmacology, 2010, 127(1), 7-10.
5. Food Research International, 2002, 35(4), 351-356.
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The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
| Size | Price(USD) | Discount |
| 5mg | Inquiry | N/A |
| 10mg | Inquiry | N/A |
| 25mg | Inquiry | N/A |
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