Curdione

Catalogue number C108562
Chemical nameCurdione
CAS Number13657-68-6
Synonyms(3S,6E,10S)-6,10-dimethyl-3-propan-2-ylcyclodec-6-ene-1,4-dione
Molecular WeightC15H24O2
Formula236.3
Purity98%
Physical DescriptionCryst.
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications

Curdione plays an important role in the CYP3A4 inhibitory activity and curdione might inhibit the activity by accelerating the degradation of CYP3A4. curdione might inhibit the activity of CYP3A4 by increasing its degradation.


Curdione may be a candidate for anti-inflammatory and cancer chemopreventive agents.
Curdione with the inhibitory effect on the production of prostaglandin E2 in lipopolysaccharide (LPS)-stimulated mouse macrophage RAW 264.7 cells in a concentration-dependent manner (IC50 = 1.1 μM).

References1. Journal of Chromatography A, 2005, 1070(1-2), 207-210.
2. Enzyme and Microbial Technology, 2006, 38(3-4), 367-371.
3. Archives of Pharmacal Research, 2007, 30(10), 1236-1239.
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Curdione
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SizePrice(USD)Discount
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10mgInquiryN/A
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