6,7-Dihydroxycoumarin

Catalogue number C108531
Chemical name6,7-Dihydroxycoumarin
CAS Number305-01-1
Synonyms6,7-dihydroxy-1-benzopyran-2-one; Esculetin; Cichorigenin
Molecular WeightC9H6O4
Formula178.1
Purity98%
Physical DescriptionYellow cryst.
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications6,7-dihydroxycoumarin also known as esculetin. Esculetin-containing preparations used systemically can have an anticoagulant effect and might interact with anticoagulent drugs such as warfarin.
This compound is used in some sunscreens, but there is evidence that it acts as a photosensitizer for DNA damage. The sodium salt of its methyl-derivative is used in dermatology for the treatment of varicose veins.
It has the ability to quench the inner fluorescence of bovine serum albumin.
References1. Gerontology, 1998, 44(1), 21-25.
2. J. Med. Chem., 1971, 14(2), 167-169.
3. Appl. Environ. Microbiol. August, 1983, 46(2), 468-474.
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6,7-Dihydroxycoumarin
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